【1】 Hypertension: long term hypertension may damage the vascular health of the brain
doi：10.1161/HYPERTENSIONAHA.120.15073
Recently, in a research report published in the international journal hypertention, scientists from the University of Michigan Medical School and other institutions found that long-term high blood pressure may increase the risk of small and medium-sized vascular damage in the brain, which is often directly related to dementia and stroke risk; for a long time, we all know that high blood pressure can lead to stroke, but in the past, only studies have been conducted Linking hypertension to the risk of Alzheimer's disease, in this latest study, researchers focused on how hypertension affects cerebral small vessel disease, the most frequent cerebrovascular disease in stroke and dementia patients.
In this study, the researchers studied 1686 adults who did not suffer from stroke or dementia at the beginning of the study and analyzed the participants' data. The researchers measured their blood pressure in middle-aged and old age, and performed brain MRIs scans to check for brain microbleeds in different parts of the brain, the accumulation of small and medium-sized blood products in brain tissues, and brain tissue death These problems are the symptoms of cerebral small vessel disease.
【2】 BMJ: drinking milk can reduce the risk of diabetes and hypertension
doi：10.1136/bmjdrc-2019-000826
The incidence rate of hypertension and diabetes is rising in the United States. A recent international study found that more dairy products, especially whole milk products, were associated with lower blood pressure and lower incidence rate of diabetes.
Nearly 150000 volunteers from 21 countries (including Africa, Asia, Europe, and North and South America) participated in the study. Participants ranged in age from 35 to 70. In the study, published in the journal BMJ open Diabetes Research & care, researchers used questionnaires to understand participants' food intake throughout the year. Participants outlined the amount of food they ate in a specific type of food, including milk, yogurt, cheese and dairy products made from milk. In addition, dairy products are further classified as full fat or low-fat. The researchers also considered the participants' medical history, prescription, blood pressure, waist circumference and glucose and fat levels, as well as educational level, which are important for the diagnosis of type 2 diabetes.
【3】 EhJ NEJM: hypertension or increased risk of death from covid-19 infection
doi：10.1093/eurheartj/ehaa433 doi：10.1056/NEJMoa2006923
Recently, in a study published in the European Heart Journal, scientists from Xijing Hospital and other institutions found that compared with patients without hypertension, hypertensive patients had twice the risk of death from covid-19 infection. In addition, hypertension patients who did not take drugs to control blood pressure might have a higher risk of death due to covid-19 infection
In this paper, the data of 2866 patients admitted to Wuhan huoshenshan hospital from February 5 to March 15, 2020 were analyzed. Among them, 850 patients (29.5%) had a history of hypertension According to Professor Fei, 34 (4%) of 850 hypertensive patients died of covid-19 infection, while 22 (1.1%) of 2027 non hypertensive patients died of covid-19 infection. After adjusting for factors such as age, gender and other medical conditions, the researchers found that hypertensive patients had a 2.12 times higher risk of dying from covid-19 than non hypertensive patients.
【4】 Neurology: is hypertension easy to affect brain health at night?
doi：10.1212/WNL.0000000000009316
Most people's blood pressure drops at night, which doctors call "hypotension.". But for people with high blood pressure, their nighttime blood pressure will remain unchanged or even rise. A new study published in the journal Neurology shows that hypertension and increased blood pressure may be more likely to occur in the brain region associated with hypertension.
These results provide more evidence that vascular risk factors are important in promoting memory problems, and that efforts such as maintaining a healthy weight, being active and having a healthy diet can effectively prevent the potential effects of hypertension, the researchers said. "The study involved 435 people with an average age of 59 who participated in an aging study in Venezuela. Their blood pressure was monitored at home with a device for 24 hours, every 15 minutes during the day and every 30 minutes at night. They also performed brain scans to look for areas of the brain associated with impaired white matter hyperplasia. The participants also tested memory and other thinking abilities.
【5】 Circulation: low fiber diet leads to hypertension
doi：10.1161/CIRCULATIONAHA.119.043081
Recently, a study by Monash University scientists confirmed for the first time that a low fiber diet may lead to high blood pressure. If left untreated, high blood pressure can lead to stroke, myocardial infarction, stiffness of the heart's arteries and muscles, and kidney stiffness, thereby reducing its function. Hypertension is also the most common risk factor for cardiovascular disease. In the study, published in the journal Circulation, the authors tested the difference between a high and low resistant starch diet using a mouse model. Resistant starch is a kind of fiber food, which can resist gastrointestinal digestion until it reaches the large intestine and is absorbed by probiotics.
The results showed that mice fed a low fiber diet were more likely to develop hypertension. After that, the researchers through the sterile mice fecal transplantation experiment showed that the low fiber diet caused by intestinal microbial ecological environment changes is the direct cause of hypertension. Hypertension remains a major risk factor for cardiovascular death, the researchers said. A fiber deficient diet is associated with the prevalence of hypertension, but the study reveals the role of intestinal flora in it
Source: Progressive- charlestown.com
【6】 Experi Physiol: scientists hope to develop a new treatment for hypertension
doi：10.1113/EP087924
In a study published in the international journal empirical physiology, scientists from Boston University School of Medicine found that the key to treating hypertension may be those who can resist hypertension even if they eat high salt food. In the UK, a quarter of adults are affected by high blood pressure. At present, there are more than 1.1 billion hypertensive patients in the world. Hypertension is one of the biggest global public health problems that have not been solved yet. At the same time, hypertension is also the main cause of many diseases, including chronic kidney disease, stroke and heart disease.
Some people's blood pressure will soar after eating a high salt diet, while some people will tolerate salt. Even after high salt diet, there will be no change in blood pressure. One way to combat blood pressure problem is to simulate how these people avoid hypertension. In the paper, the researchers revealed how cells in specific areas of the hypothalamus control salt tolerance mechanisms, and found a special structural change in these cells that may help alter the body's response to salt.
【7】 Cardiovasc res: gum disease is associated with a higher risk of hypertension
doi：10.1093/cvr/cvz201
People with gum disease (periodontitis) are more likely to develop high blood pressure (hypertension), according to a study recently published in the Journal cardiovascal research. Professor Francesco d'aiuto of the Eastman Dental Institute, University of London, said: "we found that the more severe periodontitis, the higher the risk of hypertension. The results suggest that people with gum disease should understand their own risk and make recommendations on lifestyle changes to prevent hypertension, such as exercise and healthy eating.
Hypertension affects 30-45% of adults and is the leading cause of premature death worldwide, while periodontitis affects more than 50% of the world's population. Hypertension is a major preventable cause of cardiovascular disease, and periodontitis is associated with an increased risk of heart disease and stroke. "Hypertension may be the cause of heart attack and stroke in patients with periodontitis. Previous studies have shown that there is a link between periodontitis and hypertension, and dental treatment may improve blood pressure, but so far, the results are inconclusive.
【8】 Our heart J supply: stunned! About 50% of the population may not be aware that they have high blood pressure
doi：10.1093/eurheartj/suz076
Recently, in a research report published in the international journal European Heart Journal supplies, scientists from Western Australia University and other institutions found that in Australia, 50% of patients with hypertension may not realize that they have been sick. Hypertension is the largest cause of death from cardiovascular disease in the world and affects the health of about 6 million Australian adults.
In this study, the researchers studied 3817 adults. Among them, 31.2% of them had hypertension, and only half of them knew their condition. Among the treated individuals, 40% of them still had blood pressure higher than the standard value, while those who smoked, drank alcohol or had cerebrovascular diseases were more at risk of elevated blood pressure. Researcher Markus Schlaich said that although there are many effective treatments for hypertension, only half of the affected individuals will be able to be treated, and only 60% of the people receiving treatment can have their blood pressure controlled.
【9】 Hypertension: low dose radiation increases the risk of hypertension
doi：10.1161/HYPERTENSIONAHA.118.11719
Long term exposure to low doses of ionizing radiation increases the risk of high blood pressure, according to a study of Russian nuclear power plant workers published in the journal hypertension of the American Heart Association. Uncontrolled high blood pressure can lead to serious health problems such as heart attack, stroke, heart failure, etc.
Early studies have linked high-dose radiation exposure with increased risk of cardiovascular disease and death from these diseases. The study is the first to find an increased risk of high-dose ionizing radiation among a large number of workers who have been exposed for many years. The study includes the first large-scale project in Russia
【10】 ELife: scientists hope to develop new targeted drug therapy for hypertension
doi：10.7554/eLife.42628
Recently, in a research report published in the International Journal eLife, scientists from the health science research center of the University of Tennessee identified a key molecule in the process of blood pressure regulation. By turning off the function of this molecule, the blood pressure of rats can be effectively reduced.
The study ends scientists' uncertainty about the effect of the molecule on hypertension, which now affects millions of people around the world and is a major risk factor for heart attacks and strokes. Blood pressure is partially controlled by muscle cells in the body's vascular wall. These muscle cells carry special proteins called transient receptor potential channels (TRP channels), which can promote the movement of sodium and calcium. There are about 13 different TRP channels in arterial muscle cells. At present, researchers do not know whether these channels control normal blood pressure or help promote high blood pressure The occurrence of pressure.